Soluble kit receptor in human serum

Soluble kit receptor in human serum.

c-kit encodes the transmembrane receptor tyrosine kinase (Kit) for the recently described ligand stem cell factor (SCF). We have developed an enzyme-linked immunosorbent assay for measuring soluble human Kit and we have used the assay to show high levels of soluble Kit in human serum. The distribution of soluble Kit levels was investigated among 112 normal human serum donors. The mean serum lev...

Serum Level of Soluble CD226 Receptor in Healthy Individuals is Highly Variable and Associated with Age

Soluble collagen in human serum.

Soluble collagen-like components in whole human serum and in serum fractions obtained after filtration on Sephadex G-zoo or after sucrose density gradient centrifugation were analyzed by micro-immunodiffusion and by immunoelectrophoresis. Antiserum to human skin collagen served as the reagent for the detection of the antigen. The collagen-like components were shown to exist in at least z, and p...

Preparation of human serum albumin microspheres (MSA) kit for lung imaging in Iran [Persian]

Radiolabeled Microspheres of human serum albumin (MSA) is of great importance in the analysis of regional lung perfusion. Preparation of MSA kit has been installed in our Division recently is carried out in two stages: 1. Production of albumin sphere particles with suitable sizes by using the spinning disk technique. 2. Formulation of MSA as a radiopharmacutical kit. So it can be labelled...

Identification and characterization of a soluble c-kit receptor produced by human hematopoietic cell lines.

Stem cell factor (SCF) triggers cell growth by binding to cell surface c-kit receptors. Soluble forms of several cytokine receptors have been described and may play a role in the modulation of cytokine activity in vivo. For these reasons, we investigated whether human hematopoietic cells produce soluble c-kit receptors. The human leukemia cell lines OCIM1 and MO7e display approximately 80,000 a...